Parasite Induced High MDA Linked to MS Disability

High levels of malondialdehyde (MDA) are present in the blood of MS patients. MDA is the most common biomarker for oxidative stress in diseases like cancer, mental health disorders, chronic obstructive pulmonary disease, asthma, cardiovascular disease[i], MS and others. It is also linked with disability in MS. This post discusses how parasites cause oxidative stress and increased MDA, how this effects disease progression and how to recover from MS by treating the parasites that cause it.

Common biochemical changes in the blood of MS patients affect the function of nerves. Increases in lactic acid, creatinine, malondialdehyde, nitrite, nitrate, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are commonly observed in MS.[ii]

Inflammation and oxidative stress are believed to play a key role in the disease process of MS and other diseases.

Inflammation is present in all chronic diseases and is the immune system’s response to a foreign invader, usually a type of parasite. The main job of immune system is to defend the body from parasites. Thus, inflammation is the war in which the immune system is battling and destroying parasites.

One of the ways in which the immune system fights parasites is through oxidative stress.

 

Oxidative Stress – the body’s reaction to infections / parasites

The immune system quickly produces reactive oxygen species (ROS) in response to parasitic infections. These are oxygen-containing compounds like hydrogen peroxide (H2O2) created to destroy parasites.

MDA is a toxic biproduct of high oxidation and ROS during inflammation.

 

What is malondialdehyde (MDA)?

MDA is produced from the breakdown of fatty acids. It has been used as a biomarker to measure oxidative stress in tissue samples from patients that are affected by a wide range of diseases.[iii] It is used to monitor disease status.

MDA is toxic to cells and DNA and increases the risk of cancer, which can all contribute to the development of diseases and aging.[iv]

One study measured blood levels of malondialdehyde (MDA) and its relation to disease and found that:[v]

  • MDA levels were much higher in patients with MS than in healthy controls, especially during a relapse.
  • MDA levels significantly correlate with increased disability as documented in the expanded disability status scale (EDSS).

 

Which parasites that are linked to MS cause increased MDA?

The immune system uses ROS as part of its defense against many different types of parasites.

Highly increased malondialdehyde (MDA) was found in patients that tested positive for malaria. This indicated an increased production of reactive oxygen species.[vi]

Candidiasis caused by different species of candida has been linked to increased oxidative stress and MDA concentrations in the blood.[vii] [viii]

There was a significant association of oxidative stress with chronic filariasis. [ix]

 

April 2024 Wellness Champion updates

 

Student #1 – started about 3 weeks ago. In the prep phase.

“I want to share that I have made good progress. I am now able to chew and swallow with every meal.

I have had 4 decent night’s sleeps.

I have enough energy to help with some meals and to get to appointments. My POTS symptoms are getting better and I drove again for the first time in 7 weeks. My brain still feels quite fuzzy at times, but better than it has. Sleep makes a difference.

As I am starting to feel better,  I have really enjoyed all the information and all that I am learning and am so thankful that you have put this all together.”

 

Student #2 – MS diagnosis. In the prep phase.

“I’m following the Live Disease Free diet carefully.

In fact, I am noticing more and more energy, I don’t struggle to get up from the wheelchair and I can stand for a few minutes with support. Even my left arm, which was completely blocked, I can now move it a little. I sleep well, at least 8 hours, and have bowel movements every day.”

 

Student #3

“I feel a reduction in the burning in my legs, the internal feeling of an inflammation response. I also feel a dramatic reduction in my brain symptoms and my sleep feels deeper.

I am also maintaining the diet with excellence.

I exercised twice last week for 20 minutes of jogging.

The symptoms in my head have reduced dramatically.

All that I am doing is helping me get to a healthier state so I can continue treating.

As I mentioned earlier, my symptoms have really reduced.

My legs have also improved.”

 

Student #4

I’m happy to report the light bulbs are turning on. I’m beginning to get a sense of the bigger picture.

I am having daily bowel movements.

I didn’t get up to pee last night!

I walked 1/2 mile 3 times in the past week using my wheelie walker. That’s a lot!

I was able to use hiking poles to walk short distances, which I haven’t done in a year!

Heart palpitations are gone.”

 

Student #5

“The last 2-3 weeks have been really good. I had 5 nights in a row where I never had to get up to pee which is a record. Have not done that in many years.

I felt really good. I am sleeping better with very few arrhythmias and no issues sleeping on my back.”

 

Student #6

“Things are going quite well. I haven’t had MS symptoms since I finished my most recent break week after treatment cycle #6.”

There is a large and ever-growing body of research that shows that MS is an infectious disease caused by a parasitic infestation. Compelling evidence of filarial worms, fungal infections, Babesia/malaria type protists and Lyme disease are some of the main culprits that have been identified in MS patients.

There is also ample evidence that the immune system is actively fighting infection through inflammation and oxidative stress. This leaves one to question why the international panel of experts that have established the 2017 McDonald criteria for diagnosing and treating MS, finds no value in exploring which infections cause MS. They refuse to look beyond the presence of lesions and antibodies that they assume are the result of the immune system attacking nerve tissue for no apparent reason.

When reviewing the last two pages of the McDonald criteria, one begins to better understand this bias as the panel is funded by the very companies that sell the expensive MS immunosuppressive maintenance disease modifying drugs.

Is this not a conflict of interest? It appears that the medical standard of care for multiple sclerosis has been hijacked and no longer serves the best interests of MS patients. It will continue to be gridlocked until MS patients become aware of the truth and make different choices in their healthcare. This is the only way things will change.

There are real solutions to recover from parasites today!

To restore health, we must focus on treating the cause of inflammation, which are parasites. First, identify the enemy (parasites), then support the body and treat the parasites while following a holistic approach. When parasitic infections are treated effectively, we can overcome inflammation or disease.

If you’re frustrated with the fact that our standard of care STILL doesn’t offer a real solution for treating MS and other diseases, then click on the link below to watch Pam Bartha’s free masterclass training and discover REAL solutions that have allowed Pam and many others to live free from MS and other diseases.

CLICK Here to watch Pam’s masterclass training

Or take the Health Blocker Quiz to see if you could have parasite infections

 

References:

https://www.mdpi.com/1420-3049/28/16/5979

[i] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597159/#:~:text=Malondialdehyde%20(MDA)%20is%20the%20most,%2C%20asthma%2C%20or%20cardiovascular%20diseases.

[ii] https://www.hindawi.com/journals/msi/2011/167156/

[iii] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457993/#:~:text=Malondialdehyde%20(MDA)%20is%20a%20compound,a%20wide%20range%20of%20diseases.

[iv] https://typeset.io/questions/what-are-the-consequences-of-having-high-levels-of-28mt8t2znb

[v] https://pubmed.ncbi.nlm.nih.gov/33895606/

[vi] https://scialert.net/fulltext/?doi=ajbs.2011.506.513#:~:text=Highly%20increased%20Malondialdehyde%20(MDA)%20activity,production%20of%20reactive%20oxygen%20species.

[vii] https://pubmed.ncbi.nlm.nih.gov/15693608/

[viii] https://www.academia.edu/72132322/In_vitro_response_of_clinical_isolates_of_Candida_species_to_oxidative_stress

[ix] https://pubmed.ncbi.nlm.nih.gov/16554077/

Almost there! Please complete this form and click the button below to gain instant access

Author Pam Bartha

Register below to reserve your spot...it's FREE!

Privacy Policy: We hate spam and promise to keep your email address safe